A novel series of 6-amino uracil base analogue were synthesized.QSAR study was used to relate the selective nonsubstrate inhibitory activity of 6-amino uracil base analogue with various physicochemical descriptors.Stepwise multiple regression analysis was performed to find out the correlation between various Back Sar Pad physicochemical descriptors
Global evaluation of taxonomic relationships and admixture within the Culex pipiens complex of mosquitoes
Abstract Background Within the Culex pipiens mosquito complex, there are Necklaces six contemporarily recognized taxa: Cx.quinquefasciatus, Cx.pipiens f.pipiens, Cx.pipiens f.molestus, Cx.pipiens pallens, Cx.australicus and Cx.globocoxitus.Many phylogenetic aspects within this complex have eluded resolution, such as the relationship of the two Aust
CB2R activation enhances tumor-associated macrophages-mediated phagocytosis of glioma cell
Background: Cannabinoid administration has demonstrated promising anti-tumor effects for glioblastoma (GBM) by inhibiting glioma cell proliferation and inducing glioma cell death.However, the impact of cannabinoids and endocannabinoid receptors on immune cells within the tumor microenvironment (TME) remains largely unexplored.Tumor-associated macro
Factors associated with frequent use of emergency-department services in a geriatric population: a systematic review
Abstract Background Frequent geriatric users of emergency departments (EDs) constitute a small group of individuals accounting for a disproportionately high number of ED visits.In addition to overcrowding, this situation might result in a less appropriate response to health needs and negative health impacts.Geriatric patients turn to EDs for a vari